CGRP targeted therapies: the latest in effective, safe migraine medication

Migraine and headache treatment has expanded dramatically in the last six years. Where previously your options were primarily limited to antidepressants, anti-seizure medications, and anti-hypertensive medications, you now have access to a new class of medications called Calcitonin gene-related peptide (CGRP) inhibitors. These drugs are safe, effective, and offer more relief on average.

Work in 60% of people with migraine

50% reduction in migraine attacks per month

Low risk of side effects

Preventive oral medication or once-monthly injections

CGRP inhibitors target the root causes of migraine, making them widely effective for a high percentage of people who use them. 70% of patients who take preventive CGRP inhibitors experience a 50% or more reduction of their migraine symptoms monthly.

Oral & nasal medications to alleviate attack symptoms

Oral and nasal CGRP inhibitors, when taken early enough, can also be used to alleviate symptoms of a migraine attack.

Access

Our certified headache specialists evaluate each patient thoroughly to determine if CGRP inhibitors are a suitable treatment for your migraine symptoms. When appropriate, our specialists will prescribe the medication and help you navigate the insurance process to ensure the cost is covered.

Man injecting self with auto-injector on thigh

FAQs

What CGRP inhibitors do you offer?

Preventive: Aimovig (erenumab), Emgality (galcanezumab), Ajovy (fremanezumab), Vyepti (eptinezumab), Nurtec (Rimegepant) every other day, Qulipta (Atogepant)

Acute: Ubrelvy (Ubrogepant), Nurtec (rimegepant), Zavzpret (Zavegepant)

What are the side effects?

Side effects of CGRP inhibitors can vary by medication, but the most common symptom seen is easily treatable constipation. Injection site reactions might occur for injectable medications, but this is rare.

Does insurance cover these medications?

Most insurances cover CGRP inhibitors with a prior authorization from your doctor or your Haven headache specialist.

How can I get started with treatment?

Your Haven headache specialist will discuss treatment options during your first appointment. Depending on what you have tried in the past, you might be a good fit right away for one of these medications, or you might need to try a few other options before starting. Some insurance companies require you to try a few other medications before prescribing a CGRP inhibitor.

How effective are these medications?

~70% of patients with migraine who try CGRPs for three months or more experience a 50% reduction in migraine symptoms. While the science is still fairly new (by medical standards), studies have proven that the effectiveness of CGRP inhibitors tends to increase the longer you are on them.

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