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Safe Migraine Medications While Breastfeeding

Safe Migraine Medications While Breastfeeding

Dr. Susan Hutchinson
March 10, 2025
5
min read

For many breastfeeding mothers, managing migraines while ensuring their baby’s safety can be challenging. Fortunately, there are migraine medications that are considered safe while breastfeeding, allowing you to find relief without compromising your baby’s health.

Understanding Medication Safety in Breastfeeding

During pregnancy, medications can pass directly to the baby through the placenta. However, when breastfeeding, the drug must pass into the mother’s bloodstream, enter the breast milk, and then be ingested by the baby. The amount of medication that reaches the infant is typically much lower than during pregnancy, which is why some medications are considered safer postpartum.

The LactMed database is a free and reliable resource where you can check the safety of specific medications for breastfeeding mothers.

Medications That Are Generally Considered Safe

💊 NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) 💊

  • Ibuprofen (Advil, Motrin) – Considered safe and commonly recommended.
  • Naproxen (Aleve) – Generally safe but should be used with caution for long-term use.
  • ⚠️ Avoid adult-strength aspirin due to the risk of Reye’s syndrome in infants.

💊 Triptans (Acute Migraine Medications) 💊

  • Sumatriptan (Imitrex) – Low transfer to breast milk; considered safe.
  • Rizatriptan (Maxalt) – Limited data, but generally considered safe.
  • Eletriptan (Relpax) – Preferred due to low milk transfer.

💊 Gepants (Newer Migraine Medications) 💊

  • Nurtec (rimegepant) – Very low levels detected in breast milk; considered safe.
  • Ubrelvy (ubrogepant) – Limited data but thought to be safe.

🤢 Anti-Nausea Medications 🤢

  • Zofran (ondansetron) – Safe and effective for nausea associated with migraines.
  • Metoclopramide (Reglan) – Can be used but may increase milk supply, so should be monitored.

Medications to Use with Caution or Avoid

  • Monoclonal Antibodies (CGRP inhibitors like Aimovig, Emgality, and Vyepti) – Limited data on breastfeeding safety; alternatives like beta blockers may be preferable.
  • Topiramate (Topamax) – May cause drowsiness and feeding difficulties in infants; should be used only if benefits outweigh risks.
  • Ergotamines (DHE, Migranal) – Not recommended as they have a long half-life and higher transfer to breast milk.

Strategies for Reducing Infant Exposure

If you are concerned about medication affecting your baby, consider these strategies:

  • Timing your dose – Take medication immediately after breastfeeding to minimize exposure.
  • Pump and Dump – Not always necessary, but an option for extra caution with certain medications.
  • Monitor your baby – Watch for changes in feeding, drowsiness, or unusual irritability.

Final Thoughts

Breastfeeding mothers don’t have to suffer through migraines without relief. There are multiple safe and effective treatment options available. If you’re unsure about the best medication for you, consult a healthcare provider or headache specialist.

At Haven Headache, our team of specialists can help create a personalized treatment plan that balances your health with your breastfeeding goals. Book an appointment today to get expert guidance and relief.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider for medical guidance tailored to your individual needs.

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